Purdue University PURDUE AGRICULTURE
FORESTRY &
NATURAL RESOURCES
 
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Maria S Sepúlveda

Assoc. Professor of Ecology of Natural Systems

Department: Forestry and Natural Resources
Phone: 765.494.3428
Fax: 765.496.2422
Office: FORS 103
E-mail: mssepulv@purdue.edu
Personal Web Page

Area of Expertise: Ecology of Natural Systems
Curriculum Vitae

 

Research Group Facilities Areas of Excellence Related Centers
Dr. Maria ("Marisol") Sepúlveda’s main area of research is ecotoxicology.  Over the last decade, she has conducted extensive research evaluating the sublethal effects of a wide-range of environmental contaminants on the physiology of numerous terrestrial and aquatic species.  For instance, she has worked with heavy metals (mercury), complex industrial mixtures (paper mill effluents), herbicides and pesticides (e.g. atrazine, dieldrin, DDT and derivatives, and toxaphene), and industrial pollutants (polychlorinated biphenyls and polyaromatic hydrocarbons).  In terms of species, although most of her work has been focused using vertebrates (including marine mammals, birds, and fishes) as animal models, Dr. Sepúlveda has recently began research with aquatic invertebrates (Hyalella and Diporeia). 

Within the field of ecotoxicology, Dr. Sepúlveda’s main area of interest involves studying the potential health effects of environmental contaminants in populations of free-ranging fish and wildlife.  Specifically, Dr. Sepúlveda’s research has focused on understanding the effects of pollutants on reproduction and early life-stage development.  Besides examining whole animal and tissue-level responses to environmental contaminants, in recent years Dr. Sepúlveda has began investigating the effects of chemicals at the sub-cellular and molecular levels.  In fact, since her arrival to Purdue, she has incorporated the use of proteomics and genomics in her research.  In collaboration with other Purdue faculty, Dr. Sepúlveda is also in the process of developing other novel biomarkers of exposure and effects to environmental stressors such as “physiomics” and “metabolomics”.

Dr. Sepúlveda also studies diseases in fish and wildlife.  Her strong background in veterinary medicine has helped her apply many diagnostic tools in the assessment and evaluation of health status in free-ranging fish and wildlife.  Dr. Sepúlveda has conducted several studies evaluating the parasitic helminthofauna and related health effects in marine mammals and aquatic birds.  She has also developed baseline hematological and blood chemistry parameters for a fish and a marine mammal species.   

Dr. Sepúlveda has over 35 peer-reviewed manuscripts published in the areas of ecotoxicology and wildlife diseases, and has presented her work at dozens of international meetings.

 

- Recent Publications

Sepúlveda, M. S., & Gonzalez-acuna, D. (2013). Comparison of heavy metals from resident Larus dominicanus and migratory Leucophaeus pipixcan from Talcahuano, Chile.. Archivos de Medicina Veterinaria.

Zenobio, J. E., Sanchez, B. C., Archuleta, L. C., & Sepúlveda, M. S. (2013). Effects and mechanisms of toxicity of triclocarban, DEET and a mixture of other pharmaceuticals on fathead minnows (Pimephales promelas).. Environmental Toxicology and Chemistry.

Hewson, I., Eaglesham, J., LaBarre, B. A., Thompson, P. D., Watkins, J., Rudstam, L., . . . Sepúlveda, M. S. (2013). Investigation of viruses associated with Diporeia spp. from the Laurentian Great Lakes and Owasco Lake, NY as a potential stressor of declining populations. Journal of Great Lakes Research, 39, 499-506.

Sepúlveda, M. S., & Kinsella, J. M. (2013). lminth collection and identification from wildlife.. Journal of Visualized Experiments.

Meyer, J. L., Rogers-Burch, S., Leet, J. K., Villeneuve, D. L., Ankley, G. T., & Sepúlveda, M. S. (2013). An evaluation of reproductive physiology in common snapping turtles (Chelydra serpentina) exposed to runoff from a concentrated animal feeding operation. Journal of Wildlife Diseases, 49, 996-999.

Freeman, J. L., Weber, G. J., & Sepúlveda, M. S. (2013). Fishing for microRNAs in Toxicology. In: microRNAs in Toxicology and Medicine. In microRNAs in Toxicology and Medicine (Vol. 1st, pp. 50-75). Sussex, UK: John Wiley & Sons Ltd.

Stensberg, M. C., Madangopal, R., Yale, G., Wei, Q., Ochoa-acuna, H., Wei, A., . . . Sepúlveda, M. S. (2013). Silver nanoparticle-specific mitotoxicity in Daphnia magna.. Nanotoxicology, 8, 833-842.

Maity, S., Jannasch, A., Adamec, J., Watkins, J. M., Nalepa, T. F., Hook, T. O., & Sepúlveda, M. S. (2013). Elucidating causes of Diporeia decline in the Great Lakes via metabolomics: Physiological responses after exposure to different stressors. Physiological and Biochemical Zoology, 86, 213-223.

Chen, S., McKinney, J. G., Nichols, K. M., & Sepúlveda, M. S. (2013). In silico prediction and in vivo validation of Daphnia pulex microRNAs.. PLoS ONE, 9, e83708.

Butler, L. R., Doll, J. C., Leet, J. K., Meyer, J. L., Moraga, P., & Sepúlveda, M. S. (2013). Impacts of sewage waste water on feminization and vitellogenin expression in male fathead minnows (Pimephales promelas) from Indiana Waters. Proceedings of the Indiana Academy of Science.

 

+ Patents

 

- Awards & Honors

• Award of Excellence, Western Association of Agricultural Experiment Station Directors, for project “W-2045: Agrochemical Impacts on Human Environmental Health: Mechanisms and Mitigation” (2013). USDA.

TEAM Award for "Zip-Trips" (2012). College of Agriculture, Purdue University.

Appointed to the Editorial of Critical Reviews in Environmental Sciences and Technology (2010). Critical Reviews in Environmental Sciences and Technology.

Appointed as Board Member for 3 years (2009). Society of Environmental Toxicology and Chemistry.

Appointed to the Editorial Board (2009). Journal of Applied Toxicology.

 

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